Dr. Francisco J. Ruiz

Areas of Specialization
Main research lines and clinical practice
Acceptance and Commitment Therapy (ACT)
Research on the efficacy and change processes of ACT across multiple clinical and health domains, and in populations of all ages.
Relational Frame Theory (RFT)
Basic and applied research on the behavioral processes involved in human language and cognition.
RNT-focused ACT Model
Innovative model that incorporates conceptualization and research in RFT and integrates it into ACT to develop briefer and more effective interventions.
Featured Publications
A selection of representative work
Prompt carefully! ChatGPT displays rule-based insensitivity to contingencies
Ruiz, F. J., Cardona-Betancourt, V.
Journal of Contextual Behavioral Science
Experimental study applying a contingency-reversal paradigm to examine rule-governed behavior in four frontier large language models (LLMs): GPT 5.2, Claude Opus 4.5, Grok 4.1 Fast, and Gemini 3 Flash. In a 2×2 factorial design (Rule × Reasoning) comprising 640 sessions, the models played a discrimination-learning task whose contingencies reversed without warning at trial 41. All four LLMs displayed rule-based insensitivity to contingencies—replicating the phenomenon documented in humans: providing a rule accelerated acquisition but reduced adaptation after reversal. The magnitude varied markedly (Claude retained higher sensitivity, 56%; GPT 5.2 and Grok barely adapted, 5-9%), differences the authors interpret in light of alignment procedures (pliance vs. tracking). Extended reasoning had a limited impact. This is the first study to demonstrate contingency insensitivity in LLMs.
Clinical Behavior Analysis and RFT: Conceptualizing Psychopathology and Its Treatment
Luciano, C., Törneke, N., Ruiz, F. J.
Oxford Handbook of ACT
Review integrating clinical behavior analysis and RFT to explain the genesis of the 'self' and the influence of relational frames on psychopathology. Addresses implications for process-based intervention and experimental evidence relevant to ACT.
Efficacy of a Two‑Session Repetitive Negative Thinking‑Focused Acceptance and Commitment Therapy (ACT) Protocol for Depression and Generalized Anxiety Disorder: A Randomized Waitlist Control Trial
Ruiz, F. J., Peña-Vargas, A., Ramírez, E. S., Suárez-Falcón, J. C., García-Martín, M. B., García-Martín, D. M., Henao, Á., Monroy-Cifuente, A., Sánchez, P. D.
Psychotherapy (APA)
Randomized trial (N=48) comparing a 2-session RNT-focused ACT protocol versus waitlist in patients with depression and/or GAD. At 1 month, the intervention produced significant reductions in emotional symptoms (d≈2.42) and 94% clinically significant change versus 9% in WL; effects were maintained at 3 months. Indicates that very brief RNT-focused interventions can be highly effective.